• The significance of the difference in the DDR binding

  2019-09-10

  The significance of the difference in the DDR2 binding specificity towards fibrillar and non-fibrillar collagens is not understood, but may imply differences in biological responses when chondrocytes bind to different collagens in the growth plate.

• The assessment process is even more difficult when Commercia

  2019-09-09

  The assessment process is even more difficult when Commercial-Off-The-Shelf (COTS) components – whose internals are partially or totally unknown – come into play.

• C PHNO has been described as a full agonist at

  2019-09-07

  [11C]-(+)-PHNO has been described as a full agonist at both D2 and D3 receptors [54,55]. [11C]-(+)-PHNO was initially developed as a PET radiotracer for imaging the high affinity state of the D2 receptor (i.e., highD2) as a means of measuring synaptic dopamine changes in response to pharmacologic challenge [56,57].

• Future analysis could consider using fixed effects also with

  2019-09-06

  Future analysis could consider using fixed effects also with the level set field, , in order to investigate which covariates explain the classification, a feature of the proposed model that we have not yet investigated.

• br Material and methods br

  2019-09-05

  Discussion The results show for the first time that DDRs may be involved in the pathogenic mechanisms of neurodegenerative diseases.

• In S cerevisiae Mek a paralog of the

  2019-09-04

  In S. cerevisiae, Mek1, a paralog of the checkpoint kinase Chk2, mediates cell-cycle arrest in response to meiotic defects (Bailis and Roeder, 2000, Xu et al., 1997).

• Information on the mechanism by which

  2019-09-03

  Information on the mechanism by which parasite infections promote ECM degradation is limited (McKerrow et al., 1983; Andrade, 1994; Lu and Lai, 2013; Thibeaux et al., 2014).

• The large body of structural knowledge that is

  2019-09-02

  The large body of structural knowledge that is currently available for CRM1 has contributed to atomic level and mechanistic understanding of many steps in the CRM1 nuclear export cycle.

• Currently approved anti obesity drugs for long term use such

  2019-08-30

  Currently approved anti-obesity drugs for long term use such as orlistat, lorcaserin and liraglutide are efficient in reduction of weight gain but are limited in usage due to their adverse effect profile and higher cost (Krentz et al., 2016; Mopuri and Islam, 2017).

• HOIP s ability to build linear Ub

  2019-08-29

  HOIP\'s ability to build linear Ub chains arises from a unique domain that follows directly after the RING2 domain, the linear ubiquitin chain-determining domain (LDD) (Fig. 1).

• Based on both the observational and

  2019-08-28

  Based on both the observational and theoretical data generated in this study, it appears that the mechanism(s) underlying lower IFM CPT1 activity is complex.

• The Wnt signaling pathway has been demonstrated

  2019-08-27

  The Wnt signaling pathway has been demonstrated to be responsible for a variety of biological processes.

• A topological property P is said to be cut

  2019-08-26

  A topological property P is said to be cut point hereditary [3] if whenever a space X has property P, then, for every there exists some separation of such that each of and has property P.

• If the unwanted objects detected by OpenComet are

  2019-08-24

  If the unwanted objects detected by OpenComet are manually deleted, and then the DNA (%) in tail is computed, the performance of the present method can be compared more effectively.

• EW-7197 br Introduction Estrogens play an important role in

  2019-08-23

  Introduction Estrogens play an important role in the EW-7197 (Arevalo et al., 2015).

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